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		<title>&#8220;Headlines&#8221; from the Future of Medicine</title>
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		<pubDate>Fri, 11 Mar 2011 19:15:30 +0000</pubDate>
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				<category><![CDATA[Future Headlines]]></category>

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		<description><![CDATA[Written by Kathryn Myronuk Passengers Exposed to Virus on Plane Donor Organ Transplants Reach Record Lows: Printed Ones Grown to Order “Locked In” Stroke Victim Controls Exoskeleton, Car, House with Implant One Nurse, One Cellphone,  800 Passengers Screened for Virus Before Landing First Robotic Surgery on Everest: Fallen Climber Required Immediate Attention Cancer Treatments Made to [...]]]></description>
			<content:encoded><![CDATA[<p><em>Written by Kathryn Myronuk</em></p>
<p><a href="#Vaccine Waiting at Arrival Gate">Passengers Exposed to Virus on Plane</a></p>
<p><a href="#Used While New One is Growing">Donor Organ Transplants Reach Record Lows: Printed Ones Grown to Order </a></p>
<p><a href="#“Locked In” Stroke Victim Controls Exoskeleton, Car, House with Implant">“Locked In” Stroke Victim Controls Exoskeleton, Car, House with Implant</a></p>
<p><a href="#One Nurse, One Cellphone,  800 Passengers Screened for Virus Before Landing">One Nurse, One Cellphone,  800 Passengers Screened for Virus Before Landing</a></p>
<p><a href="#Everest">First Robotic Surgery on Everest: Fallen Climber Required Immediate Attention</a></p>
<p><a href="#Cancer">Cancer Treatments Made to Order</a></p>
<h3><strong>_________________________________________________</strong></h3>
<p><a name="Vaccine Waiting at Arrival Gate" id="Passengers Exposed to Virus on Plane"></a><br />
<h2><strong>Passengers Exposed to Virus on Plane: Vaccine Waiting at Arrival Gate</strong></h2>
<p><a href="http://futuremed2020.com/beta/wp-content/uploads/2011/03/airtraffic.jpg"><img src="http://futuremed2020.com/beta/wp-content/uploads/2011/03/airtraffic.jpg?w=300" alt="" title="Airplane Traffic" width="300" height="225" class="alignright size-medium wp-image-883" /></a><font size="3"><em>Air Circulation System Detect Mutation</em></p>
<p>Nurse’s Cell Phone Confirms Bioinformatics, data mining, nanotechnology and other devices for biosurveillance and point of care diagnostics together bring about rapid response, design and production of anti-virals and vaccines.</font></p>
<p><font size="2"><em><strong>REFERENCES:</strong></em><br />
<a href="http://www.fas.org/blog/bio/2010/05/globalizing-public-health-and-bio-surveillance/" target="_blank">Globalizing Public Health and Bio-Surveillance</a> (Panel, 2010) F. Doro et al. 2009.</p>
<p>Surfome Analysis as a Fast Track to Vaccine Discovery. July 1, 2009 Molecular &amp; Cellular Proteomics, 8, 1728-1737. Available from <a href="http://www.mcponline.org/content/8/7/1728.short" target="_blank">Molecular &amp; Cellular Proteomics</a>.</p>
<p>Michele Kutzler and David B. Weiner. DNA vaccines: ready for prime time? Nature Reviews Genetics 9, 776-788 (October 2008) | doi:10.1038/nrg2432</p>
<p>Mike May 2009. Engineering a New Business. Nature Biotechnology 27, 1112 &#8211; 1120 (2009) doi:10.1038/nbt1209-1112. Available from <a href="http://www.synbioproject.org/process/assets/files/6452/_draft/nbt-2009-12k_-_engineering_a_new_business.pdf" target="_blank">Nature America, Inc</a>.</p>
<p>Robert Carlson 2009. The changing economics of DNA synthesis. Nature Biotechnology 27, 1091 &#8211; 1094 (2009) doi:10.1038/nbt1209-1091.</p>
<h3><strong>________________________________________________________________________________________</strong></h3>
<p><a name="Used While New One is Growing" id="Donor Organ Transplants Reach Record Lows: Printed Ones Grown to Order"></a><br />
<h2><strong>Donor Organ Transplants Reach Record Lows: Printed Ones Grown to Order</strong></h2>
<p><a href="http://futuremed2020.com/beta/wp-content/uploads/2011/03/transplant.png"><img src="http://futuremed2020.com/beta/wp-content/uploads/2011/03/transplant.png?w=300" alt="" title="Transplant" width="300" height="167" class="alignright size-medium wp-image-885" /></a><font size="3"><em>Tissue Engineers Experiment with New Shapes, Sizes</em></p>
<p>Organ printing and the ability to build organs from scratch ex-vivo (including vasculature) are a major aspect of regenerative medicine, used to address the huge unmet need for organ transplantation.</font></p>
<p><font size="2"><em><strong>REFERENCES:</strong></em><br />
Ringeisen, Spargo and Wu, Eds. Cell and Organ Printing. <a href="http://www.springer.com/biomed/book/978-90-481-9144-4" target="_blank">Book, 2010 e00p. ISBN: 978-90-481-9144-4</a>.</p>
<p>Kristine Rustad et al. 2010. Strategies for organ level tissue engineering. Organogenesis. 2010 Jul–Sep; 6(3): 151–157. Available from: <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946046/" target="_blank">Organogenesis</a>.</p>
<h3><strong>________________________________________________________________________________________</strong></h3>
<p><a name="“Locked In” Stroke Victim Controls Exoskeleton, Car, House with Implant" id="“Locked In” Stroke Victim Controls Exoskeleton, Car, House with Implant"></a><br />
<h2><strong>“Locked In” Stroke Victim Controls Exoskeleton, Car, House with Implant</strong></h2>
<p><a href="http://futuremed2020.com/beta/wp-content/uploads/2011/03/robotic.png"><img src="http://futuremed2020.com/beta/wp-content/uploads/2011/03/robotic.png?w=300" alt="" title="Robotic" width="300" height="198" class="alignright size-medium wp-image-887" /></a><font size="3">Brain Computer Interfaces (BCI): Fully implanted BCI to control devices such as computers and wheelchairs just by thinking, and deep brain stimulation to alter the course of Parkinson&#8217;s, depression and other diseases.</font></p>
<p><font size="2"><em><strong>REFERENCES:</strong></em><br />
Jonathan R. Wolpaw 2010. Brain–Computer Interface Research Comes of Age: Traditional Assumptions Meet Emerging Realities. Journal of Motor Behavior Volume 42, Number 6 / November-December 2010.</p>
<p>Daniel P. Ferris 2009. The exoskeletons are here. Journal of Neuroengineering and Rehabilitation 2009 June 9;6:17. See also: Daniel Ferris, Editor. Thematic Series: Robotic Lower Limb Exoskeletons. Available from the <a href="http://www.jneuroengrehab.com/series/robotic_lower_limb_exoskeletons" target="_blank">Journal of Neuroengineering and Rehabilitation</a>.</p>
<p>Ferris, Sawicki and Daley 2007. A Physiologist&#8217;s Perspective on Robotic Exoskeletons for Human Locomotion. International Journal of Humanoid Robotics 2007 September; 4(3): 507–528. Available from the <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185037" target="_blank">NIH</a> and the <a href="http://www-personal.umich.edu/~ferrisdp/Ferris_IJHR_2007.pdf" target="_blank">International Journal of Humanoid Robotics</a>.</p>
<p>USF News 2009. Researchers Develop &#8220;Brain-Controlled&#8221; Wheelchair Robotic Arm, January 28, 2009. Available from the <a href="http://usfweb3.usf.edu/absolutenm/templates/?a=1130&amp;z=41" target="_blank">University of Southern Florida.</a></p>
<p>&nbsp;</p>
<h3><strong>________________________________________________________________________________________</strong></h3>
<p><a name="One Nurse, One Cellphone,  800 Passengers Screened for Virus Before Landing" id="One Nurse, One Cellphone,  800 Passengers Screened for Virus Before Landing"></a><br />
<h2><strong>One Nurse, One Cellphone,  800 Passengers Screened for Virus Before Landing</strong></h2>
<p><font size="3"><em>After Virus Detected, Lab-on-a-Chip Used to Find Patient Zero</em></p>
<p><a href="http://futuremed2020.com/beta/wp-content/uploads/2011/03/microfluidics.jpg"><img class="alignright size-medium wp-image-650" title="microfluidics" src="http://futuremed2020.com/beta/wp-content/uploads/2011/03/microfluidics.jpg?w=300" alt="" width="300" height="241" /></a>Lab-on-a-chip technologies allow for rapid, point of care disease detection and treatments. Examples: sepsis detection (short term) and treatment (medium term), noninvasive fetal cell sampling to replace amniocentesis (medium term), nanofiltration replacement for dialysis (long term).</font><br />
<br /></br></p>
<p><font size="2"><em><strong>REFERENCES:</strong></em><br />
Grifantini, K. Lab-on-a-Chip Made of Paper:  Paper-based microfluidic devices could yield cheap, disposable diagnostic tests. Technology Review. May 14, 2008. Available from: <a href="http://www.technologyreview.com/biotech/20771/">http://www.technologyreview.com/biotech/20771/</a>.</span></p>
<p><font size="2">Farmer,  Melanie A. Columbia engineer designs handheld device used to diagnose illness. PhysOrg.com. October 15, 2010. Available from <a href="http://www.physorg.com/news/2010-10-columbia-handheld-device-illness.html" target="_blank">PhysOrg</a>.</p>
<p>Engineering team invents lab-on-a-chip for fast, inexpensive blood tests: Next step will turn blood testing into a smartphone application. EurekAlert! January 11, 2011. Available from <a href="http://www.eurekalert.org/index.php" target="_blank">EurekaAlert!</a></font></p>
<h3><strong>________________________________________________________________________________________</strong></h3>
<p><a name="Everest" id="First Robotic Surgery on Everest: Fallen Climber Required Immediate Attention"></a><br />
<h2><strong>First Robotic Surgery on Everest: Fallen Climber Required Immediate Attention</strong></h2>
<p><font size="3"><em>Helicopter Delivers Autonomous Robotic Surgeon</em></p>
<p><a href="http://futuremed2020.com/beta/wp-content/uploads/2011/03/robotic-surgery.jpg"><img class="alignleft size-medium wp-image-651" title="Robotic surgery" src="http://futuremed2020.com/beta/wp-content/uploads/2011/03/robotic-surgery.jpg?w=300" alt="" width="300" height="220" /></a>Increasingly autonomous, minimally invasive robotic assisted surgery, and integrated telemedicine will enable remote medical supervision, and superior clinical outcomes for many procedures where the hands of the surgeon will be supplanted of those of a robot (initially human controlled, but increasingly with more and more autonomy). </font><br />
<br /></br></p>
<p><font size="2"><em><strong>REFERENCES:</strong></em><br />
Cleveland Clinic Unveils Top 10 Medical Innovations for 2011. Available from<a href="http://my.clevelandclinic.org/media_relations/cleveland-clinic-unveils-top-10-medical-innovations-for-2011.aspx" target="_blank"> Cleveland Clinic</a>.</p>
<p>&#8220;Telehealth monitoring for heart failure patients&#8221;. Nguan, C et al. Pre-clinical remote telesurgery trial of a da Vinci telesurgery prototype. <a href="http://www3.interscience.wiley.com/journal/121409428/abstract" target="_blank">The International Journal of Medical Robotics and Computer Assisted Surgery</a>. 4: 304–309. doi: 10.1002/rcs.210</p>
<p>Wang, Brian. Pill-size to bacteria sized robots for surgery and in-body therapies. <a href="http://nextbigfuture.com/2008/10/pill-size-to-bacteria-sized-robots-for.html" target="_blank">Next Big Future</a>, October 15 2010.</font></p>
<h3><strong>________________________________________________________________________________________</strong></h3>
<p><a name="Cancer" id="Cancer Treatments Made to Order"></a><br />
<h2><strong><strong>Cancer Treatments Made to Order</strong></strong></h2>
<p><font size="3"><em><a href="http://futuremed2020.com/beta/wp-content/uploads/2011/03/cancer-cell.jpg"><img class="alignright size-medium wp-image-675" title="Cancer cell" src="http://futuremed2020.com/beta/wp-content/uploads/2011/03/cancer-cell.jpg?w=300" alt="" width="300" height="237" /></a>Personalized Treatment for Cancer with frequent monitoring, captures and sequences malignant cells, detects changes and optimizes therapy</em></p>
<p>With exponentially cheaper genomics (and the ability to fully sequence a tumor and compare to the individuals normal genome), with point of care proteomics, each patients cancer can be fully characterized at the molecular level, and a cocktail of most effective, cancer specific drugs prescribed. Cancer stem cells are targets for specific, less toxic and curative chemotherapies. A paradigm shift in treatment of malignancies,<br />
integrated with advances in detection, imaging, biomarker measures,<br />
and disease tracking leads to increasing prevention and cure rates.</font></p>
<p><font size="2"><em><strong>REFERENCES:</strong></em><br />
Massachusetts General Hospital. Improved device provides more rapid, comprehensive analysis of circulating tumor cells. March 31, 2010. Available from <a href="http://www.mgh.harvard.edu/about/pressrelease.aspx?id=1220" target="_blank">MGH.</a></p>
<p>Caltech Media Relations. Caltech-led Team Provides Proof in Humans of RNA Interference Using Targeted Nanoparticles: Researchers unveil scientific results from siRNA Phase I clinical trial in cancer patients. March 21, 2010. Available from the <a href="http://media.caltech.edu/press_releases/13334" target="_blank">California Institute of Technology</a>.<br />
Cleveland Clinic. Cleveland Clinic Unveils Top 10 Medical Innovations for 2011.  November 3, 2010. Available from <a href="http://my.clevelandclinic.org/media_relations/cleveland-clinic-unveils-top-10-medical-innovations-for-2011.aspx" target="_blank">Cleveland Clinic</a></p>
<p>Singularity Hub. A Smartphone-Enabled Device that Detects Cancer in Under an Hour. March 10, 2011. Available on <a href="http://singularityhub.com/2011/03/10/a-smartphone-enabled-device-that-detects-cancer-in-under-an-hour/" target="_blank"> Singularity Hub</a>.</p>
<p>National Cancer Institute. First therapeutic cancer vaccine approved by the FDA. Carmen Phillips. March 4, 2010. Available on <a href="http://www.cancer.gov/ncicancerbulletin/050410/page2" target="_blank">National Cancer Institute</a></font></p>
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